Sounds like you are running into this issue
It’s reporting that extension helper is not loaded which indicates:
<script src="https://extension-files.twitch.tv/helper/v1/twitch-ext.min.js"></script>
Is missing, it could be missing as the index/panel HTML was not loaded as it’s in a folder in the extensions directory instead of in the root. But you got a good hit on panel.html apparently
1 Failed to load resource: the server responded with a status of 404 ()
vendor-5182f7f13a7032c44bf7.js
Did this file not get uploaded or was it renamed and not updated in the panel.html